21 products · Average rating: 3.8/5 · 161 reviews
21 Biotech products
1849 bio designs microbes enabling cheap metal extraction allowing miners to unlock value from low quality copper and gold ores. Surprisingly, the mining industry is one of the largest scale users of biotech in the world with biomining processes accounting for ~1% of global copper production. Biomining is ultra-low cost, running around ~$1/ton of ore vs ~$7/ton for conventional processes. Unfortunately, while biomining is cheap, it can’t be applied to over 80% of copper ores, leaving vast resources without profitable extraction methods. An estimated ~$800B of copper sit today in waste materials and stockpiles with negative unit economics. While a great deal of effort has been spent on optimizing microbial metal extraction processes, very little effort has been spent on optimizing the microbes themselves. To change that, we’re creating new biotech tools and platforms applied directly to the types of biology most relevant to miners. This enables us to develop new microbes and tackle some of the most difficult problems in biomining, unlocking billions in value from unprofitable resources while being more environmentally friendly than conventional processes. We’re world class microbial engineers. We met while doing our PhDs in synthetic biology, where we spent our time applying and developing the most advanced bioengineering technologies to engineer living cells.
SynsoryBio is creating next generation, protein therapeutics that sense where they are in the body and only activate at diseased tissue. This technology platform has the potential to expand the therapeutic window of highly potent drugs and apply to many diseases such as cancer and autoimmune disorders.
Angstrom AI builds GenAI-based molecular simulations to substitute wet lab experiments in the pre-clinical drug development pipeline. We are a team of 2 PhD's and 2 Professors from the University of Cambridge who decided to start a company together after we realised how to combine breakthoughs in our research in quantum-accurate models of physics and generative AI models. Our Biotech/Pharma clients can verify the efficacy and safety of new drug candidates using our computer simulations, which match the accuracy of wet lab experiments, but are over 100x faster. We achieve this accuracy by constraining our genAI-based simulations to obey the laws of physics, avoiding the hallucinations seen in other GenAI technologies. Since joining YC, Angstrom AI has developed the first physically accurate gen-AI based simulation of multiple molecules interacting. We have published the first molecule water solubility results with accuracy within the error range of wet lab experiments. We have also kicked-off a 150K pilot project with a pharma company to apply our tech to estimating solubility in their drug development pipeline.
Yoneda Labs provides software to help chemists optimise reactions. When chemists make a drug or a material, we help them figure out the best reaction parameters such as temperature, concentration and catalyst. When Jan was working at chemical labs, he experienced the struggle of spending weeks guessing reaction conditions. We then started experimenting with ML to speed up the process. Now, as a team of three friends from the University of Cambridge, we’ve spent the last month combining our domain expertise in Computer Science, Machine Learning and Chemistry to develop state of the art models for reaction optimisation. Although ML is becoming well established in other fields, current chemical models generalise poorly and require lots of programming experience. We make our models easily accessible to chemists in the lab. Finding the right conditions quickly allows pharmaceutical companies to test more drugs, and finding better optima makes manufacturing process cheaper and more environmentally friendly.
You can think of Stempad as a Notion for science. It is the world's first true pen-and-paper alternative to fast scientific writing and collaborating. Quickly switch between different forms of technical visualization with the ease of a whiteboard and the convenience of your keyboard. Stempad allows you to share your work, collaborate in real time, store your data, annotate, write papers, plan, takes notes, create presentations, and so much more. Our vision is to make it easier and faster for students and scientists to digitize and share their scientific ideas.
Artos is an AI-based document-drafting platform that helps life sciences companies turn their data into critical documents in minutes. These submissions currently take months and are the final hurdle before life sciences companies are allowed to sell their product.
We are developing cancer therapeutics using small molecules that inhibit immune suppression. Our drugs engage the immune system to aggressively fight tumors. Our therapeutic portfolio addresses a range of solid tumors, starting with mesothelioma.
We are building the next generation of deep-learning models for enzyme design to slash the cost of chemical manufacturing. The $6 trillion chemical industry is flawed: It produces 20% of industrial greenhouse gases, and is responsible for 15% of global energy usage. Enzymes offer a far more sustainable alternative to chemical synthesis and have already revolutionised how a select few chemicals are produced. The problem is each enzyme takes years of trial and error to develop. Our enzyme models learn the principles of catalysis, allowing us to design enzymes for each reaction, in days not years. We currently have $4.3M of LOIs and have completed our first $20k contract.
Finding new cures requires seeing what and where the abnormal molecules are in a diseased tissue, but current tools see less than 1% of those molecules. Biocartesian combines microscopy and new chemistries to see 50X more, offering unprecedented insights into disease biology and new therapies.
🦠🤖 We use our computational models to make next-generation antibiotics that outcompete bacterial evolution and precisely target pathogenic bacteria, without harming good microbes or human cells. ☠️ Current antibiotics stop working because bacteria evolve resistance to them. This makes drug-resistant bacteria a looming global health crisis - already killing more people than malaria and AIDS and it is getting exponentially worse 📈. 🧬 Our approach leverages co-evolutionary protein-protein interaction datasets combined with AI to forecast bacterial mutations and create ‘future-proof’ antibiotics, addressing antibiotic resistance before it develops. This changes the game for how frequently society will need to make new antibiotics and how long our new antibiotics will be able to treat patients 👩⚕️. We are a team of biochemists and evolutionary biologists who met at the University of Oxford.
Metofico provides a no-code data analysis tool tailored for the life sciences. Our platform enables life scientists to analyse complex/massive datasets and extract necessary insights without needing advanced programming skills. This accessibility helps both researchers new to data science and experts save months of work. Metofico aims to be the leading centralized platform for data analysis in life science research, covering a wide range of applications from brain activity analysis (like photometry and EEG) to AI-powered detection and tracking of research animals. Our vision is to accelerate research processes and enhance the quality of research outputs across the board. By streamlining complex data analysis and making it more accessible, we’re committed to driving forward scientific discoveries and innovation.
Proteins power everything from the cells in your body to creating materials you rely on every day, but until now, we’ve been forced to discover their functions by trial and error. Designing a new therapeutic can take decades and billions of dollars, and even our best industrial catalysts work at a snail’s pace compared to their theoretical optimums. Anthrogen is changing that. By training massive AI foundation models on protein sequences and structures, we’ve unlocked the ability to generate, on demand, completely novel molecular machines with atomic-level precision. Simply describe the function you need, and our platform imagines the peptide or protein that will deliver it. We're building models to speed up billions of years of evolution into the span of an afternoon's worth of compute. The result? New-to-nature therapies, ultra-efficient catalysts for sustainable manufacturing, and a whole new frontier of molecular innovation, designed as precisely as any cutting-edge aircraft or microchip.
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