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Angstrom AI builds GenAI-based molecular simulations to substitute wet lab experiments in the pre-clinical drug development pipeline. We are a team of 2 PhD's and 2 Professors from the University of Cambridge who decided to start a company together after we realised how to combine breakthoughs in our research in quantum-accurate models of physics and generative AI models. Our Biotech/Pharma clients can verify the efficacy and safety of new drug candidates using our computer simulations, which match the accuracy of wet lab experiments, but are over 100x faster. We achieve this accuracy by constraining our genAI-based simulations to obey the laws of physics, avoiding the hallucinations seen in other GenAI technologies. Since joining YC, Angstrom AI has developed the first physically accurate gen-AI based simulation of multiple molecules interacting. We have published the first molecule water solubility results with accuracy within the error range of wet lab experiments. We have also kicked-off a 150K pilot project with a pharma company to apply our tech to estimating solubility in their drug development pipeline.

Tamarind Bio is a website and API which allows scientists to use computational biology tools at scale using a simple interface. On Tamarind, scientists can use ML models like AlphaFold to design and simulate molecules by simply selecting inputs instead of or setting up a high performance computing environment or dealing with DevOps. Our tools are used by thousands researchers in large pharma companies, top biotechs, and academic institutions. We currently focus on models in protein design and engineering, including for antibodies/therapeutics and enzymes. Get in touch at [email protected]